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SMILES: Cc1c(CCCCc2ccccc2)nc2ccc(F)cc2c1C(O)=O

InChI Key: InChIKey=SXTJZCJVYYJADE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284865   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50284865
PNG
(6-Fluoro-3-methyl-2-(4-phenyl-butyl)-quinoline-4-c...)
Show SMILES Cc1c(CCCCc2ccccc2)nc2ccc(F)cc2c1C(O)=O
Show InChI InChI=1S/C21H20FNO2/c1-14-18(10-6-5-9-15-7-3-2-4-8-15)23-19-12-11-16(22)13-17(19)20(14)21(24)25/h2-4,7-8,11-13H,5-6,9-10H2,1H3,(H,24,25)
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Article
>500n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.

Bioorg Med Chem Lett 5: 1549-1554 (1995)


Article DOI: 10.1016/0960-894X(95)00252-O
BindingDB Entry DOI: 10.7270/Q29K4B55
More data for this
Ligand-Target Pair