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SMILES: CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)c1ccccc1)C(O)=O

InChI Key: InChIKey=WYRYVFKNAKYOEK-PHGOAHNDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284948   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50284948
PNG
((S)-2-[(S)-2-((S)-2-{[(S)-2-((R)-2,6-Diamino-hexan...)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)c1ccccc1)C(O)=O
Show InChI InChI=1S/C27H44N6O6S2/c1-16(2)21(33(3)26(37)25(40)32-22(34)18(29)12-8-9-14-28)24(36)31-20(17-10-6-5-7-11-17)23(35)30-19(27(38)39)13-15-41-4/h5-7,10-11,16,18-21,25,40H,8-9,12-15,28-29H2,1-4H3,(H,30,35)(H,31,36)(H,32,34)(H,38,39)/t18-,19+,20+,21+,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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KEGG
PC cid
PC sid
UniChem

Similars
Article
n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of farnesyl transferase (FTase) of rat brain

Bioorg Med Chem Lett 5: 1779-1784 (1995)


Article DOI: 10.1016/0960-894X(95)00314-J
BindingDB Entry DOI: 10.7270/Q2H41RDH
More data for this
Ligand-Target Pair