BindingDB logo
myBDB logout

BDBM50284996 2-Methylamino-3-[2'-(5-oxo-4,5-dihydro-[1,2,4]oxadiazol-3-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid::CHEMBL291689

SMILES: CNc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1

InChI Key: InChIKey=WFJHFWZQMPSBNU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284996   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50284996
PNG
(2-Methylamino-3-[2'-(5-oxo-4,5-dihydro-[1,2,4]oxad...)
Show SMILES CNc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1
Show InChI InChI=1S/C24H19N5O4/c1-25-23-26-19-8-4-7-18(22(30)31)20(19)29(23)13-14-9-11-15(12-10-14)16-5-2-3-6-17(16)21-27-24(32)33-28-21/h2-12H,13H2,1H3,(H,25,26)(H,30,31)(H,27,28,32)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 260n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [125 I]-AII (0.2 nM) from bovine adrenal cortical membrane angiotensin II (AII) receptor at 10e-7 M


Bioorg Med Chem Lett 5: 1903-1908 (1995)


Article DOI: 10.1016/0960-894X(95)00319-O
BindingDB Entry DOI: 10.7270/Q26M36SM
More data for this
Ligand-Target Pair