BDBM50285163 2-{4-Butyl-2,6-dioxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,6-dihydro-2H-pyrimidin-1-ylmethyl}-benzoic acid methyl ester::CHEMBL304251

SMILES: CCCCc1cc(=O)n(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=QZLYOKHNUOFSHZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50285163 (2-{4-Butyl-2,6-dioxo-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCCCc1cc(=O)n(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C31H30N6O4/c1-3-4-10-24-18-28(38)37(20-23-9-5-6-12-26(23)30(39)41-2)31(40)36(24)19-21-14-16-22(17-15-21)25-11-7-8-13-27(25)29-32-34-35-33-29/h5-9,11-18H,3-4,10,19-20H2,1-2H3,(H,32,33,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex				Bioorg Med Chem Lett 5: 2071-2076 (1995) Article DOI: 10.1016/0960-894X(95)00370-9 BindingDB Entry DOI: 10.7270/Q2SF2W4J
					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50285163 (2-{4-Butyl-2,6-dioxo-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCCCc1cc(=O)n(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C31H30N6O4/c1-3-4-10-24-18-28(38)37(20-23-9-5-6-12-26(23)30(39)41-2)31(40)36(24)19-21-14-16-22(17-15-21)25-11-7-8-13-27(25)29-32-34-35-33-29/h5-9,11-18H,3-4,10,19-20H2,1-2H3,(H,32,33,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for binding affinity against angiotensin II receptor in rat adrenal cortex				Bioorg Med Chem Lett 5: 2071-2076 (1995) Article DOI: 10.1016/0960-894X(95)00370-9 BindingDB Entry DOI: 10.7270/Q2SF2W4J
					More data for this Ligand-Target Pair