BDBM50285166 3-Allyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-pyrimidine-2,4-dione::CHEMBL303822

SMILES: CCCc1cc(=O)n(CC=C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=ZZNGOSDWGJACFQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50285166 (3-Allyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCc1cc(=O)n(CC=C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H24N6O2/c1-3-7-19-15-22(31)29(14-4-2)24(32)30(19)16-17-10-12-18(13-11-17)20-8-5-6-9-21(20)23-25-27-28-26-23/h4-6,8-13,15H,2-3,7,14,16H2,1H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for binding affinity against angiotensin II receptor in rat adrenal cortex				Bioorg Med Chem Lett 5: 2071-2076 (1995) Article DOI: 10.1016/0960-894X(95)00370-9 BindingDB Entry DOI: 10.7270/Q2SF2W4J
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50285166 (3-Allyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCc1cc(=O)n(CC=C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H24N6O2/c1-3-7-19-15-22(31)29(14-4-2)24(32)30(19)16-17-10-12-18(13-11-17)20-8-5-6-9-21(20)23-25-27-28-26-23/h4-6,8-13,15H,2-3,7,14,16H2,1H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex				Bioorg Med Chem Lett 5: 2071-2076 (1995) Article DOI: 10.1016/0960-894X(95)00370-9 BindingDB Entry DOI: 10.7270/Q2SF2W4J
					More data for this Ligand-Target Pair