BDBM50285348 2-[4-(7-Methyl-2-propyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-pentanoic acid::CHEMBL41534

SMILES: CCCC(Oc1ccc(Cn2c(CCC)nc3c(C)ccnc23)cc1)C(O)=O

InChI Key: InChIKey=OCRZHCYMFUQPSM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50285348 (2-[4-(7-Methyl-2-propyl-imidazo[4,5-b]pyridin-3-yl...) Show SMILES CCCC(Oc1ccc(Cn2c(CCC)nc3c(C)ccnc23)cc1)C(O)=O Show InChI InChI=1S/C22H27N3O3/c1-4-6-18(22(26)27)28-17-10-8-16(9-11-17)14-25-19(7-5-2)24-20-15(3)12-13-23-21(20)25/h8-13,18H,4-7,14H2,1-3H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair