BDBM50285817 CHEMBL431592::{3-[2'-(Butoxycarbonylamino-sulfonyl)-biphenyl-4-ylmethyl]-2-butyl-4-oxo-3,4-dihydro-imidazo[4,5-c]pyridin-5-yl}-phenyl-acetic acid isopropyl ester

SMILES: CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccn(C(C(=O)OC(C)C)c4ccccc4)c(=O)c23)cc1

InChI Key: InChIKey=VNDDUGBRNUTRBI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50285817 (CHEMBL431592 | {3-[2'-(Butoxycarbonylamino-sulfony...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccn(C(C(=O)OC(C)C)c4ccccc4)c(=O)c23)cc1 Show InChI InChI=1S/C39H44N4O7S/c1-5-7-18-34-40-32-23-24-42(35(38(45)50-27(3)4)30-14-10-9-11-15-30)37(44)36(32)43(34)26-28-19-21-29(22-20-28)31-16-12-13-17-33(31)51(47,48)41-39(46)49-25-8-6-2/h9-17,19-24,27,35H,5-8,18,25-26H2,1-4H3,(H,41,46)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparation				Bioorg Med Chem Lett 5: 2665-2670 (1995) Article DOI: 10.1016/0960-894X(95)00477-B BindingDB Entry DOI: 10.7270/Q2ZW1KVW
					More data for this Ligand-Target Pair
Angiotensin II AT2 (RAT)	BDBM50285817 (CHEMBL431592 | {3-[2'-(Butoxycarbonylamino-sulfony...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccn(C(C(=O)OC(C)C)c4ccccc4)c(=O)c23)cc1 Show InChI InChI=1S/C39H44N4O7S/c1-5-7-18-34-40-32-23-24-42(35(38(45)50-27(3)4)30-14-10-9-11-15-30)37(44)36(32)43(34)26-28-19-21-29(22-20-28)31-16-12-13-17-33(31)51(47,48)41-39(46)49-25-8-6-2/h9-17,19-24,27,35H,5-8,18,25-26H2,1-4H3,(H,41,46)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity determined against angiotensin II AT2 receptor in rat adrenal medulla preparation				Bioorg Med Chem Lett 5: 2665-2670 (1995) Article DOI: 10.1016/0960-894X(95)00477-B BindingDB Entry DOI: 10.7270/Q2ZW1KVW
					More data for this Ligand-Target Pair