BDBM50285912 CHEMBL91557::[(1S,3S,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-benzoylamino)-5-phenyl-pentyl]-carbamic acid tert-butyl ester

SMILES: CC(C)(C)OC(=O)N[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1O)Cc1ccccc1

InChI Key: InChIKey=LRLOSFJDDYZMEF-RMDSEJHCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50285912 (CHEMBL91557 | [(1S,3S,4S)-1-Benzyl-3-hydroxy-4-(2-...) Show SMILES CC(C)(C)OC(=O)N[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1O)Cc1ccccc1 Show InChI InChI=1S/C30H36N2O5/c1-30(2,3)37-29(36)31-23(18-21-12-6-4-7-13-21)20-27(34)25(19-22-14-8-5-9-15-22)32-28(35)24-16-10-11-17-26(24)33/h4-17,23,25,27,33-34H,18-20H2,1-3H3,(H,31,36)(H,32,35)/t23-,25-,27-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against purified HIV protease				Bioorg Med Chem Lett 5: 2725-2728 (1995) Article DOI: 10.1016/0960-894X(95)00462-3 BindingDB Entry DOI: 10.7270/Q26973JN
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