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BDBM50286017 CHEMBL319603::{[6-(4-Fluoro-phenyl)-3-((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazole-7-carbonyl)-indole-1-carbonyl]-amino}-acetic acid

SMILES: OC(=O)CNC(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1

InChI Key: InChIKey=QYQLNIMXEAWVMK-MUUNZHRXSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286017   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50286017
PNG
(CHEMBL319603 | {[6-(4-Fluoro-phenyl)-3-((R)-3-pyri...)
Show SMILES OC(=O)CNC(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C29H21FN4O4S/c30-20-6-3-17(4-7-20)18-5-8-21-23(15-34(24(21)12-18)29(38)32-14-26(35)36)27(37)22-9-11-33-25(22)16-39-28(33)19-2-1-10-31-13-19/h1-13,15,28H,14,16H2,(H,32,38)(H,35,36)/t28-/m1/s1
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Similars
Article
 130n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for platelet activating factor receptor using [3H]-PAF in rabbit platelet membranes

Bioorg Med Chem Lett 5: 2913-2918 (1995)


Article DOI: 10.1016/0960-894X(95)00511-Q
BindingDB Entry DOI: 10.7270/Q2NC6157
More data for this
Ligand-Target Pair