BDBM50286248 CHEMBL4168030

SMILES: Cl.CCCCCc1cc(O)c(C(=O)NCC(O)=O)c2ncnn12

InChI Key: InChIKey=KCQKVGYUMLHKFH-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50286248 (CHEMBL4168030) Show SMILES Cl.CCCCCc1cc(O)c(C(=O)NCC(O)=O)c2ncnn12 Show InChI InChI=1S/C14H18N4O4/c1-2-3-4-5-9-6-10(19)12(13-16-8-17-18(9)13)14(22)15-7-11(20)21/h6,8,19H,2-5,7H2,1H3,(H,15,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Japan Tobacco Inc. Curated by ChEMBL					Assay Description Inhibition of PHD2 in human Hep3B cells assessed as increase in EPO release after 24 hrs by ELISA				ACS Med Chem Lett 8: 1320-1325 (2017) Article DOI: 10.1021/acsmedchemlett.7b00404 BindingDB Entry DOI: 10.7270/Q21N83N8
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50286248 (CHEMBL4168030) Show SMILES Cl.CCCCCc1cc(O)c(C(=O)NCC(O)=O)c2ncnn12 Show InChI InChI=1S/C14H18N4O4/c1-2-3-4-5-9-6-10(19)12(13-16-8-17-18(9)13)14(22)15-7-11(20)21/h6,8,19H,2-5,7H2,1H3,(H,15,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Japan Tobacco Inc. Curated by ChEMBL					Assay Description Inhibition of human HIF-PHD2 assessed as reduction in HIF1-alpha binding to VBC complex using biotin-labeled HIF1-alpha peptide as substrate preincub...				ACS Med Chem Lett 8: 1320-1325 (2017) Article DOI: 10.1021/acsmedchemlett.7b00404 BindingDB Entry DOI: 10.7270/Q21N83N8
					More data for this Ligand-Target Pair