BDBM50286249 CHEMBL4159929

SMILES: Cl.CCc1c(O)c(C(=O)NCC(O)=O)c2ncnn2c1CC

InChI Key: InChIKey=CHKGPWAPCYYGMT-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50286249 (CHEMBL4159929) Show SMILES Cl.CCc1c(O)c(C(=O)NCC(O)=O)c2ncnn2c1CC Show InChI InChI=1S/C13H16N4O4/c1-3-7-8(4-2)17-12(15-6-16-17)10(11(7)20)13(21)14-5-9(18)19/h6,20H,3-5H2,1-2H3,(H,14,21)(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
Japan Tobacco Inc. Curated by ChEMBL					Assay Description Inhibition of PHD2 in human Hep3B cells assessed as increase in EPO release after 24 hrs by ELISA				ACS Med Chem Lett 8: 1320-1325 (2017) Article DOI: 10.1021/acsmedchemlett.7b00404 BindingDB Entry DOI: 10.7270/Q21N83N8
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50286249 (CHEMBL4159929) Show SMILES Cl.CCc1c(O)c(C(=O)NCC(O)=O)c2ncnn2c1CC Show InChI InChI=1S/C13H16N4O4/c1-3-7-8(4-2)17-12(15-6-16-17)10(11(7)20)13(21)14-5-9(18)19/h6,20H,3-5H2,1-2H3,(H,14,21)(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Japan Tobacco Inc. Curated by ChEMBL					Assay Description Inhibition of human HIF-PHD2 assessed as reduction in HIF1-alpha binding to VBC complex using biotin-labeled HIF1-alpha peptide as substrate preincub...				ACS Med Chem Lett 8: 1320-1325 (2017) Article DOI: 10.1021/acsmedchemlett.7b00404 BindingDB Entry DOI: 10.7270/Q21N83N8
					More data for this Ligand-Target Pair