BDBM50286895 1-(3,3-Dimethyl-2-oxo-butyl)-5-(1H-pyrazol-3-yl)-3-[(m-tolylamino-methyl)-amino]-1,3-dihydro-benzo[e][1,4]diazepin-2-one::CHEMBL345880
SMILES: Cc1cccc(NCNC2N=C(c3ccn[nH]3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1
InChI Key: InChIKey=YTGBKAHCXKZZPK-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CCKBR (RAT) | BDBM50286895 (1-(3,3-Dimethyl-2-oxo-butyl)-5-(1H-pyrazol-3-yl)-3...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards gastrin/Cholecystokinin type B receptor from rat brain using [125I]-CCK-8 as the radioligand | Bioorg Med Chem Lett 6: 55-58 (1996) Article DOI: 10.1016/0960-894X(95)00557-A BindingDB Entry DOI: 10.7270/Q2CJ8DGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50286895 (1-(3,3-Dimethyl-2-oxo-butyl)-5-(1H-pyrazol-3-yl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards Cholecystokinin type A receptor from rat pancreas using [I125]-L-364,718 as the radioligand | Bioorg Med Chem Lett 6: 55-58 (1996) Article DOI: 10.1016/0960-894X(95)00557-A BindingDB Entry DOI: 10.7270/Q2CJ8DGT | |||||||||||
More data for this Ligand-Target Pair |