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Enter Data

BDBM50287089 CHEMBL278287::N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide

SMILES: CN(C(=O)c1ccccc1)c1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key: InChIKey=HTCQGVPSEDIYST-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50287089
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50287089 (CHEMBL278287 \| N-Methyl-N-[4-methyl-3-(4-pyridin-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of serine/threonine kinase(PKC-alpha)				Bioorg Med Chem Lett 6: 1221-1226 (1996) Article DOI: 10.1016/0960-894X(96)00197-7 BindingDB Entry DOI: 10.7270/Q2348KBG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50287089 (CHEMBL278287 \| N-Methyl-N-[4-methyl-3-(4-pyridin-3...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of tyrosine kinase Epidermal growth factor receptor				Bioorg Med Chem Lett 6: 1221-1226 (1996) Article DOI: 10.1016/0960-894X(96)00197-7 BindingDB Entry DOI: 10.7270/Q2348KBG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-dependent protein kinase (PKA) (Homo sapiens (Human))	BDBM50287089 (CHEMBL278287 \| N-Methyl-N-[4-methyl-3-(4-pyridin-3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of serine/threonine kinase(PKA)				Bioorg Med Chem Lett 6: 1221-1226 (1996) Article DOI: 10.1016/0960-894X(96)00197-7 BindingDB Entry DOI: 10.7270/Q2348KBG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50287089 (CHEMBL278287 \| N-Methyl-N-[4-methyl-3-(4-pyridin-3...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of tyrosine kinase(PDGF-R)				Bioorg Med Chem Lett 6: 1221-1226 (1996) Article DOI: 10.1016/0960-894X(96)00197-7 BindingDB Entry DOI: 10.7270/Q2348KBG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50287089 (CHEMBL278287 \| N-Methyl-N-[4-methyl-3-(4-pyridin-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of serine/threonine kinase(PKC-delta)				Bioorg Med Chem Lett 6: 1221-1226 (1996) Article DOI: 10.1016/0960-894X(96)00197-7 BindingDB Entry DOI: 10.7270/Q2348KBG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair