null

SMILES: [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6](=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])P([#8])([#8])=O

InChI Key: InChIKey=MXRXVIWCQICXLB-WUZNFZNHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50287117 ((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6](=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])P([#8])([#8])=O |w:16.17| Show InChI InChI=1S/C27H40NO6P/c1-20(2)11-9-12-21(3)13-10-14-22(4)17-18-25(35(31,32)33)26(29)28-24(27(30)34-5)19-23-15-7-6-8-16-23/h6-8,11,13,15-16,18,22,24H,9-10,12,14,17,19H2,1-5H3,(H,28,29)(H2,31,32,33)/b21-13+,25-18?/t22?,24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Farnesyltransferase from bovine brain				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50287117 ((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6](=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])P([#8])([#8])=O |w:16.17| Show InChI InChI=1S/C27H40NO6P/c1-20(2)11-9-12-21(3)13-10-14-22(4)17-18-25(35(31,32)33)26(29)28-24(27(30)34-5)19-23-15-7-6-8-16-23/h6-8,11,13,15-16,18,22,24H,9-10,12,14,17,19H2,1-5H3,(H,28,29)(H2,31,32,33)/b21-13+,25-18?/t22?,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of squalene synthase from rat liver microsomes				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair