BDBM50287141 3-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-propionic acid::CHEMBL25341

SMILES: OC(=O)CCNC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key: InChIKey=ZXQUHVRIMPPGIY-FXDYGKIASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50287141 (3-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...) Show SMILES OC(=O)CCNC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C29H33N2O7P/c32-27(33)16-17-30-28(34)25(18-22-10-4-1-5-11-22)21-39(36,37)26(19-23-12-6-2-7-13-23)31-29(35)38-20-24-14-8-3-9-15-24/h1-15,25-26H,16-21H2,(H,30,34)(H,31,35)(H,32,33)(H,36,37)/t25?,26-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50287141 (3-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...) Show SMILES OC(=O)CCNC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C29H33N2O7P/c32-27(33)16-17-30-28(34)25(18-22-10-4-1-5-11-22)21-39(36,37)26(19-23-12-6-2-7-13-23)31-29(35)38-20-24-14-8-3-9-15-24/h1-15,25-26H,16-21H2,(H,30,34)(H,31,35)(H,32,33)(H,36,37)/t25?,26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair