BDBM50287150 2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-methyl-pentanoic acid::CHEMBL24919

SMILES: CCC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O

InChI Key: InChIKey=IVJNQRXSUQUWRX-KEKDFHOJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50287150 (2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...) Show SMILES CCC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-3-23(2)29(31(36)37)34-30(35)27(19-24-13-7-4-8-14-24)22-42(39,40)28(20-25-15-9-5-10-16-25)33-32(38)41-21-26-17-11-6-12-18-26/h4-18,23,27-29H,3,19-22H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)(H,39,40)/t23?,27?,28-,29?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50287150 (2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...) Show SMILES CCC(C)C(NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C32H39N2O7P/c1-3-23(2)29(31(36)37)34-30(35)27(19-24-13-7-4-8-14-24)22-42(39,40)28(20-25-15-9-5-10-16-25)33-32(38)41-21-26-17-11-6-12-18-26/h4-18,23,27-29H,3,19-22H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)(H,39,40)/t23?,27?,28-,29?/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair