BDBM50287481 3-[5-(4-Fluoro-benzenesulfonylamino)-3-imidazol-1-ylmethyl-2-methyl-indol-1-yl]-propionic acid::CHEMBL45075

SMILES: Cc1c(Cn2ccnc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2n1CCC(O)=O

InChI Key: InChIKey=QPRIPFDEBNVCAH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50287481 (3-[5-(4-Fluoro-benzenesulfonylamino)-3-imidazol-1-...) Show SMILES Cc1c(Cn2ccnc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2n1CCC(O)=O Show InChI InChI=1S/C22H21FN4O4S/c1-15-20(13-26-11-9-24-14-26)19-12-17(4-7-21(19)27(15)10-8-22(28)29)25-32(30,31)18-5-2-16(23)3-6-18/h2-7,9,11-12,14,25H,8,10,13H2,1H3,(H,28,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human platelet microsomal TXA2 synthase				Bioorg Med Chem Lett 6: 1691-1696 (1996) Article DOI: 10.1016/0960-894X(96)00299-5 BindingDB Entry DOI: 10.7270/Q27P8ZBS
					More data for this Ligand-Target Pair