BDBM50288002 5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-ethyl-benzenesulfonamide::CHEMBL78830

SMILES: CCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C

InChI Key: InChIKey=JXCXAVJWSVRLGZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50288002 (5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-ethyl-ben...) Show SMILES CCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C13H15BrN2O3S/c1-4-10-5-6-11(14)7-12(10)20(17,18)16-13-8(2)9(3)15-19-13/h5-7,16H,4H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50288002 (5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-ethyl-ben...) Show SMILES CCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C13H15BrN2O3S/c1-4-10-5-6-11(14)7-12(10)20(17,18)16-13-8(2)9(3)15-19-13/h5-7,16H,4H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair