BDBM50288082 CHEMBL79692::[2-Carbamoyl-1-(2-isopropylamino-4-oxo-4H-benzo[d][1,3]oxazin-7-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester

SMILES: CC(C)Nc1nc2cc(NC(=O)C(CC(N)=O)NC(=O)OCc3ccccc3)ccc2c(=O)o1

InChI Key: InChIKey=NHOZUFKCZWUNKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50288082 (CHEMBL79692 | [2-Carbamoyl-1-(2-isopropylamino-4-o...) Show SMILES CC(C)Nc1nc2cc(NC(=O)C(CC(N)=O)NC(=O)OCc3ccccc3)ccc2c(=O)o1 Show InChI InChI=1S/C23H25N5O6/c1-13(2)25-22-27-17-10-15(8-9-16(17)21(31)34-22)26-20(30)18(11-19(24)29)28-23(32)33-12-14-6-4-3-5-7-14/h3-10,13,18H,11-12H2,1-2H3,(H2,24,29)(H,25,27)(H,26,30)(H,28,32)	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).				Bioorg Med Chem Lett 6: 2463-2466 (1996) Article DOI: 10.1016/0960-894X(96)00455-6 BindingDB Entry DOI: 10.7270/Q2F47P4R
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