BDBM50288084 CHEMBL49391::[(S)-1-(4-Oxo-4H-benzo[d][1,3]oxazin-2-yl)-ethyl]-carbamic acid benzyl ester

SMILES: C[C@H](NC(=O)OCc1ccccc1)c1nc2ccccc2c(=O)o1

InChI Key: InChIKey=XNGNCPKMCGZSLB-LBPRGKRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50288084 (CHEMBL49391 | [(S)-1-(4-Oxo-4H-benzo[d][1,3]oxazin...) Show SMILES C[C@H](NC(=O)OCc1ccccc1)c1nc2ccccc2c(=O)o1 Show InChI InChI=1S/C18H16N2O4/c1-12(19-18(22)23-11-13-7-3-2-4-8-13)16-20-15-10-6-5-9-14(15)17(21)24-16/h2-10,12H,11H2,1H3,(H,19,22)/t12-/m0/s1	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration for peptidolytic activity against herpes simplex type-1 (HSV-1) protease at 10 uM.				Bioorg Med Chem Lett 7: 1733-1738 (1997) Article DOI: 10.1016/S0960-894X(97)00300-4 BindingDB Entry DOI: 10.7270/Q23778RS
					More data for this Ligand-Target Pair
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50288084 (CHEMBL49391 | [(S)-1-(4-Oxo-4H-benzo[d][1,3]oxazin...) Show SMILES C[C@H](NC(=O)OCc1ccccc1)c1nc2ccccc2c(=O)o1 Show InChI InChI=1S/C18H16N2O4/c1-12(19-18(22)23-11-13-7-3-2-4-8-13)16-20-15-10-6-5-9-14(15)17(21)24-16/h2-10,12H,11H2,1H3,(H,19,22)/t12-/m0/s1	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).				Bioorg Med Chem Lett 6: 2463-2466 (1996) Article DOI: 10.1016/0960-894X(96)00455-6 BindingDB Entry DOI: 10.7270/Q2F47P4R
					More data for this Ligand-Target Pair