BDBM50288088 5,8-Dichloro-2-ethoxy-benzo[d][1,3]oxazin-4-one::CHEMBL420389

SMILES: CCOc1nc2c(Cl)ccc(Cl)c2c(=O)o1

InChI Key: InChIKey=MTCHUPSYKUKIOI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50288088 (5,8-Dichloro-2-ethoxy-benzo[d][1,3]oxazin-4-one | ...) Show SMILES CCOc1nc2c(Cl)ccc(Cl)c2c(=O)o1 Show InChI InChI=1S/C10H7Cl2NO3/c1-2-15-10-13-8-6(12)4-3-5(11)7(8)9(14)16-10/h3-4H,2H2,1H3	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).				Bioorg Med Chem Lett 6: 2463-2466 (1996) Article DOI: 10.1016/0960-894X(96)00455-6 BindingDB Entry DOI: 10.7270/Q2F47P4R
					More data for this Ligand-Target Pair