BDBM50288090 CHEMBL79772::[(S)-1-(5-Chloro-4-oxo-4H-benzo[d][1,3]oxazin-2-yl)-ethyl]-carbamic acid benzyl ester

SMILES: C[C@H](NC(=O)OCc1ccccc1)c1nc2cccc(Cl)c2c(=O)o1

InChI Key: InChIKey=BGQSTIUKAKOYRE-NSHDSACASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50288090 (CHEMBL79772 | [(S)-1-(5-Chloro-4-oxo-4H-benzo[d][1...) Show SMILES C[C@H](NC(=O)OCc1ccccc1)c1nc2cccc(Cl)c2c(=O)o1 Show InChI InChI=1S/C18H15ClN2O4/c1-11(20-18(23)24-10-12-6-3-2-4-7-12)16-21-14-9-5-8-13(19)15(14)17(22)25-16/h2-9,11H,10H2,1H3,(H,20,23)/t11-/m0/s1	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).				Bioorg Med Chem Lett 6: 2463-2466 (1996) Article DOI: 10.1016/0960-894X(96)00455-6 BindingDB Entry DOI: 10.7270/Q2F47P4R
					More data for this Ligand-Target Pair