BDBM50288102 CHEMBL45496::[(S)-1-(5-Methyl-4-oxo-4H-benzo[d][1,3]oxazin-2-yl)-ethyl]-carbamic acid benzyl ester

SMILES: C[C@H](NC(=O)OCc1ccccc1)c1nc2cccc(C)c2c(=O)o1

InChI Key: InChIKey=PGOIRDQOPJUJMY-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50288102 (CHEMBL45496 | [(S)-1-(5-Methyl-4-oxo-4H-benzo[d][1...) Show SMILES C[C@H](NC(=O)OCc1ccccc1)c1nc2cccc(C)c2c(=O)o1 Show InChI InChI=1S/C19H18N2O4/c1-12-7-6-10-15-16(12)18(22)25-17(21-15)13(2)20-19(23)24-11-14-8-4-3-5-9-14/h3-10,13H,11H2,1-2H3,(H,20,23)/t13-/m0/s1	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration for peptidolytic activity against herpes simplex type-1 (HSV-1) protease at 10 uM.				Bioorg Med Chem Lett 7: 1733-1738 (1997) Article DOI: 10.1016/S0960-894X(97)00300-4 BindingDB Entry DOI: 10.7270/Q23778RS
					More data for this Ligand-Target Pair
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50288102 (CHEMBL45496 | [(S)-1-(5-Methyl-4-oxo-4H-benzo[d][1...) Show SMILES C[C@H](NC(=O)OCc1ccccc1)c1nc2cccc(C)c2c(=O)o1 Show InChI InChI=1S/C19H18N2O4/c1-12-7-6-10-15-16(12)18(22)25-17(21-15)13(2)20-19(23)24-11-14-8-4-3-5-9-14/h3-10,13H,11H2,1-2H3,(H,20,23)/t13-/m0/s1	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).				Bioorg Med Chem Lett 6: 2463-2466 (1996) Article DOI: 10.1016/0960-894X(96)00455-6 BindingDB Entry DOI: 10.7270/Q2F47P4R
					More data for this Ligand-Target Pair