BDBM50288277 3-(4-Propyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL329890
SMILES: CCCc1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br
InChI Key: InChIKey=LNLVEJQUXLDABL-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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EDNRB (Homo sapiens (Human)) | BDBM50288277![]() (3-(4-Propyl-phenyl)-thiophene-2-sulfonic acid (4-b...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 8.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for binding affinity against Endothelin B receptor | Bioorg Med Chem Lett 6: 2651-2656 (1996) Article DOI: 10.1016/S0960-894X(96)00496-9 BindingDB Entry DOI: 10.7270/Q24M94HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50288277![]() (3-(4-Propyl-phenyl)-thiophene-2-sulfonic acid (4-b...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for binding affinity against Endothelin A receptor | Bioorg Med Chem Lett 6: 2651-2656 (1996) Article DOI: 10.1016/S0960-894X(96)00496-9 BindingDB Entry DOI: 10.7270/Q24M94HV | |||||||||||
More data for this Ligand-Target Pair |