null

SMILES: CS(=O)(=O)c1ccc(cc1)-c1c(nc2sccn12)-c1ccc(F)c(F)c1

InChI Key: InChIKey=LPFFZAPRSCUBPF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50289297 (6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1c(nc2sccn12)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C18H12F2N2O2S2/c1-26(23,24)13-5-2-11(3-6-13)17-16(21-18-22(17)8-9-25-18)12-4-7-14(19)15(20)10-12/h2-10H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cellstransfected with human cyclooxygenase-...				Bioorg Med Chem Lett 7: 47-52 (1997) Article DOI: 10.1016/S0960-894X(96)00580-X BindingDB Entry DOI: 10.7270/Q2FN166R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289297 (6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1c(nc2sccn12)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C18H12F2N2O2S2/c1-26(23,24)13-5-2-11(3-6-13)17-16(21-18-22(17)8-9-25-18)12-4-7-14(19)15(20)10-12/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cellstransfected with human cyclooxygenase-...				Bioorg Med Chem Lett 7: 47-52 (1997) Article DOI: 10.1016/S0960-894X(96)00580-X BindingDB Entry DOI: 10.7270/Q2FN166R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289297 (6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1c(nc2sccn12)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C18H12F2N2O2S2/c1-26(23,24)13-5-2-11(3-6-13)17-16(21-18-22(17)8-9-25-18)12-4-7-14(19)15(20)10-12/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo ability of the compound to inhibit cyclooxygenase-2 enzyme in human whole blood was determined				Bioorg Med Chem Lett 7: 47-52 (1997) Article DOI: 10.1016/S0960-894X(96)00580-X BindingDB Entry DOI: 10.7270/Q2FN166R
					More data for this Ligand-Target Pair