BDBM50289383 4-Amino-5-chloro-2-methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL26758

SMILES: COc1ccccc1N1CCN(CCNC(=O)c2cc(Cl)c(N)cc2OC)CC1

InChI Key: InChIKey=LHXBLQLSBOWGSX-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50289383 (4-Amino-5-chloro-2-methoxy-N-{2-[4-(2-methoxy-phen...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cc(Cl)c(N)cc2OC)CC1 Show InChI InChI=1S/C21H27ClN4O3/c1-28-19-6-4-3-5-18(19)26-11-9-25(10-12-26)8-7-24-21(27)15-13-16(22)17(23)14-20(15)29-2/h3-6,13-14H,7-12,23H2,1-2H3,(H,24,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cerebral cortex				Bioorg Med Chem Lett 7: 1327-1330 (1997) Article DOI: 10.1016/S0960-894X(97)00218-7 BindingDB Entry DOI: 10.7270/Q2P55NJG
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50289383 (4-Amino-5-chloro-2-methoxy-N-{2-[4-(2-methoxy-phen...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cc(Cl)c(N)cc2OC)CC1 Show InChI InChI=1S/C21H27ClN4O3/c1-28-19-6-4-3-5-18(19)26-11-9-25(10-12-26)8-7-24-21(27)15-13-16(22)17(23)14-20(15)29-2/h3-6,13-14H,7-12,23H2,1-2H3,(H,24,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 from human Dopamine receptor D4.2 expressed in baculovirus Sf9 cells				Bioorg Med Chem Lett 7: 1327-1330 (1997) Article DOI: 10.1016/S0960-894X(97)00218-7 BindingDB Entry DOI: 10.7270/Q2P55NJG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50289383 (4-Amino-5-chloro-2-methoxy-N-{2-[4-(2-methoxy-phen...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2cc(Cl)c(N)cc2OC)CC1 Show InChI InChI=1S/C21H27ClN4O3/c1-28-19-6-4-3-5-18(19)26-11-9-25(10-12-26)8-7-24-21(27)15-13-16(22)17(23)14-20(15)29-2/h3-6,13-14H,7-12,23H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 of rat corpora striata synaptic membranes				Bioorg Med Chem Lett 7: 1327-1330 (1997) Article DOI: 10.1016/S0960-894X(97)00218-7 BindingDB Entry DOI: 10.7270/Q2P55NJG
					More data for this Ligand-Target Pair