BDBM50289658 CHEMBL45609::[(S)-2-Carbamoyl-1-(4-oxo-4H-thieno[3,2-d][1,3]oxazin-2-yl)-ethyl]-carbamic acid benzyl ester

SMILES: NC(=O)C[C@H](NC(=O)OCc1ccccc1)c1nc2ccsc2c(=O)o1

InChI Key: InChIKey=VCEZQMIASDINEN-LBPRGKRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289658   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50289658 (CHEMBL45609 | [(S)-2-Carbamoyl-1-(4-oxo-4H-thieno[...) Show SMILES NC(=O)C[C@H](NC(=O)OCc1ccccc1)c1nc2ccsc2c(=O)o1 Show InChI InChI=1S/C17H15N3O5S/c18-13(21)8-12(15-19-11-6-7-26-14(11)16(22)25-15)20-17(23)24-9-10-4-2-1-3-5-10/h1-7,12H,8-9H2,(H2,18,21)(H,20,23)/t12-/m0/s1	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration for peptidolytic activity against herpes simplex type-1 (HSV-1) protease at 10 uM.				Bioorg Med Chem Lett 7: 1733-1738 (1997) Article DOI: 10.1016/S0960-894X(97)00300-4 BindingDB Entry DOI: 10.7270/Q23778RS
					More data for this Ligand-Target Pair