BDBM50289661 CHEMBL45791::[(S)-2-Methyl-1-(4-oxo-4H-thieno[3,2-d][1,3]oxazin-2-yl)-propyl]-carbamic acid benzyl ester

SMILES: CC(C)[C@H](NC(=O)OCc1ccccc1)c1nc2ccsc2c(=O)o1

InChI Key: InChIKey=FUQPSKOYLOJFMA-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 1 protease (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50289661 (CHEMBL45791 | [(S)-2-Methyl-1-(4-oxo-4H-thieno[3,2...) Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)c1nc2ccsc2c(=O)o1 Show InChI InChI=1S/C18H18N2O4S/c1-11(2)14(16-19-13-8-9-25-15(13)17(21)24-16)20-18(22)23-10-12-6-4-3-5-7-12/h3-9,11,14H,10H2,1-2H3,(H,20,22)/t14-/m0/s1	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration for peptidolytic activity against herpes simplex type-1 (HSV-1) protease at 10 uM.				Bioorg Med Chem Lett 7: 1733-1738 (1997) Article DOI: 10.1016/S0960-894X(97)00300-4 BindingDB Entry DOI: 10.7270/Q23778RS
					More data for this Ligand-Target Pair