BDBM50289948 2-Dimethylamino-N-[5-methyl-4-oxo-2-(1-phenyl-ethylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide::CHEMBL65483

SMILES: C[C@@H](Nc1nc2ccc(NC(=O)CN(C)C)c(C)c2c(=O)o1)c1ccccc1

InChI Key: InChIKey=BZJQWZIPYSIFCK-CQSZACIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymotrypsinogen B (Homo sapiens (Human))	BDBM50289948 (2-Dimethylamino-N-[5-methyl-4-oxo-2-(1-phenyl-ethy...) Show SMILES C[C@@H](Nc1nc2ccc(NC(=O)CN(C)C)c(C)c2c(=O)o1)c1ccccc1 Show InChI InChI=1S/C21H24N4O3/c1-13-16(23-18(26)12-25(3)4)10-11-17-19(13)20(27)28-21(24-17)22-14(2)15-8-6-5-7-9-15/h5-11,14H,12H2,1-4H3,(H,22,24)(H,23,26)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against human chymotrypsin				Bioorg Med Chem Lett 7: 2105-2108 (1997) Article DOI: 10.1016/S0960-894X(97)00368-5 BindingDB Entry DOI: 10.7270/Q2RR1Z6P
					More data for this Ligand-Target Pair
Human rhinovirus A protease (Human rhinovirus B)	BDBM50289948 (2-Dimethylamino-N-[5-methyl-4-oxo-2-(1-phenyl-ethy...) Show SMILES C[C@@H](Nc1nc2ccc(NC(=O)CN(C)C)c(C)c2c(=O)o1)c1ccccc1 Show InChI InChI=1S/C21H24N4O3/c1-13-16(23-18(26)12-25(3)4)10-11-17-19(13)20(27)28-21(24-17)22-14(2)15-8-6-5-7-9-15/h5-11,14H,12H2,1-4H3,(H,22,24)(H,23,26)/t14-/m1/s1	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against human cytomegalovirus protease variant expressing a beta galactosidase reporter gene				Bioorg Med Chem Lett 7: 2105-2108 (1997) Article DOI: 10.1016/S0960-894X(97)00368-5 BindingDB Entry DOI: 10.7270/Q2RR1Z6P
					More data for this Ligand-Target Pair