BindingDB logo
myBDB logout

BDBM50289950 4-Methoxy-N-[5-methyl-4-oxo-2-(1-phenyl-ethylamino)-4H-benzo[d][1,3]oxazin-6-yl]-benzenesulfonamide::CHEMBL63420

SMILES: COc1ccc(cc1)S(=O)(=O)Nc1ccc2nc(N[C@H](C)c3ccccc3)oc(=O)c2c1C

InChI Key: InChIKey=JIKNMJSADNYLOE-MRXNPFEDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289950   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chymotrypsinogen B


(Homo sapiens (Human))
BDBM50289950
PNG
(4-Methoxy-N-[5-methyl-4-oxo-2-(1-phenyl-ethylamino...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc2nc(N[C@H](C)c3ccccc3)oc(=O)c2c1C
Show InChI InChI=1S/C24H23N3O5S/c1-15-20(27-33(29,30)19-11-9-18(31-3)10-12-19)13-14-21-22(15)23(28)32-24(26-21)25-16(2)17-7-5-4-6-8-17/h4-14,16,27H,1-3H3,(H,25,26)/t16-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 3.60E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against human chymotrypsin


Bioorg Med Chem Lett 7: 2105-2108 (1997)


Article DOI: 10.1016/S0960-894X(97)00368-5
BindingDB Entry DOI: 10.7270/Q2RR1Z6P
More data for this
Ligand-Target Pair
Human rhinovirus A protease


(Human rhinovirus B)
BDBM50289950
PNG
(4-Methoxy-N-[5-methyl-4-oxo-2-(1-phenyl-ethylamino...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc2nc(N[C@H](C)c3ccccc3)oc(=O)c2c1C
Show InChI InChI=1S/C24H23N3O5S/c1-15-20(27-33(29,30)19-11-9-18(31-3)10-12-19)13-14-21-22(15)23(28)32-24(26-21)25-16(2)17-7-5-4-6-8-17/h4-14,16,27H,1-3H3,(H,25,26)/t16-/m1/s1
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 270n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against human cytomegalovirus protease variant expressing a beta galactosidase reporter gene


Bioorg Med Chem Lett 7: 2105-2108 (1997)


Article DOI: 10.1016/S0960-894X(97)00368-5
BindingDB Entry DOI: 10.7270/Q2RR1Z6P
More data for this
Ligand-Target Pair