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SMILES: C\C(CC\C=C(/C)COC(=O)c1cccc(c1)C(=O)c1ccccc1)=C/COP([O-])(=O)OP([O-])([O-])=O

InChI Key: InChIKey=GDNLVYWUVLSRJS-KKEAHIQDSA-K

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289981   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Saccharomyces cerevisiae (Baker's yeast))
BDBM50289981
PNG
(Prenyl pyrophosphate analogue | {[(2E,6E)-8-[(3-be...)
Show SMILES C\C(CC\C=C(/C)COC(=O)c1cccc(c1)C(=O)c1ccccc1)=C/COP([O-])(=O)OP([O-])([O-])=O
Show InChI InChI=1S/C24H28O10P2/c1-18(14-15-33-36(30,31)34-35(27,28)29)8-6-9-19(2)17-32-24(26)22-13-7-12-21(16-22)23(25)20-10-4-3-5-11-20/h3-5,7,9-14,16H,6,8,15,17H2,1-2H3,(H,30,31)(H2,27,28,29)/p-3/b18-14+,19-9+
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Similars

Article
380n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of yeast Farnesyl transferase


Bioorg Med Chem Lett 7: 2125-2130 (1997)


Article DOI: 10.1016/S0960-894X(97)00373-9
BindingDB Entry DOI: 10.7270/Q2542P3X
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Saccharomyces cerevisiae (Baker's yeast))
BDBM50289981
PNG
(Prenyl pyrophosphate analogue | {[(2E,6E)-8-[(3-be...)
Show SMILES C\C(CC\C=C(/C)COC(=O)c1cccc(c1)C(=O)c1ccccc1)=C/COP([O-])(=O)OP([O-])([O-])=O
Show InChI InChI=1S/C24H28O10P2/c1-18(14-15-33-36(30,31)34-35(27,28)29)8-6-9-19(2)17-32-24(26)22-13-7-12-21(16-22)23(25)20-10-4-3-5-11-20/h3-5,7,9-14,16H,6,8,15,17H2,1-2H3,(H,30,31)(H2,27,28,29)/p-3/b18-14+,19-9+
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of yeast Farnesyl transferase


Bioorg Med Chem Lett 7: 2125-2130 (1997)


Article DOI: 10.1016/S0960-894X(97)00373-9
BindingDB Entry DOI: 10.7270/Q2542P3X
More data for this
Ligand-Target Pair