BDBM50290957 CHEMBL94426::N-{2-Benzo[1,3]dioxol-5-yl-2-[3-(4-chloro-phenyl)-6-oxo-5,6-dihydro-4H-pyridazin-1-yl]-acetyl}-4-isopropyl-benzenesulfonamide

SMILES: CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(N1N=C(CCC1=O)c1ccc(Cl)cc1)c1ccc2OCOc2c1

InChI Key: InChIKey=PVWVCMKAQWLCMB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin receptor ET-B (Sus scrofa)	BDBM50290957 (CHEMBL94426 | N-{2-Benzo[1,3]dioxol-5-yl-2-[3-(4-c...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(N1N=C(CCC1=O)c1ccc(Cl)cc1)c1ccc2OCOc2c1 |c:18| Show InChI InChI=1S/C28H26ClN3O6S/c1-17(2)18-5-10-22(11-6-18)39(35,36)31-28(34)27(20-7-13-24-25(15-20)38-16-37-24)32-26(33)14-12-23(30-32)19-3-8-21(29)9-4-19/h3-11,13,15,17,27H,12,14,16H2,1-2H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to endothelin B receptor of porcine kidney membranes				Bioorg Med Chem Lett 7: 275-280 (1997) Article DOI: 10.1016/S0960-894X(96)00617-8 BindingDB Entry DOI: 10.7270/Q2QF8SWT
					More data for this Ligand-Target Pair
EDNRA (RAT)	BDBM50290957 (CHEMBL94426 | N-{2-Benzo[1,3]dioxol-5-yl-2-[3-(4-c...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(N1N=C(CCC1=O)c1ccc(Cl)cc1)c1ccc2OCOc2c1 |c:18| Show InChI InChI=1S/C28H26ClN3O6S/c1-17(2)18-5-10-22(11-6-18)39(35,36)31-28(34)27(20-7-13-24-25(15-20)38-16-37-24)32-26(33)14-12-23(30-32)19-3-8-21(29)9-4-19/h3-11,13,15,17,27H,12,14,16H2,1-2H3,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to the endothelin A receptor of rat aorta membranes				Bioorg Med Chem Lett 7: 275-280 (1997) Article DOI: 10.1016/S0960-894X(96)00617-8 BindingDB Entry DOI: 10.7270/Q2QF8SWT
					More data for this Ligand-Target Pair