BDBM50291083 (9H-Purin-6-yl)-(3,4,5-trimethoxy-phenyl)-amine; hydrochloride::CHEMBL538528

SMILES: COc1cc(Nc2ncnc3nc[nH]c23)cc(OC)c1OC

InChI Key: InChIKey=HVFVYEOXOKZJOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50291083 ((9H-Purin-6-yl)-(3,4,5-trimethoxy-phenyl)-amine; h...) Show SMILES COc1cc(Nc2ncnc3nc[nH]c23)cc(OC)c1OC Show InChI InChI=1S/C14H15N5O3/c1-20-9-4-8(5-10(21-2)12(9)22-3)19-14-11-13(16-6-15-11)17-7-18-14/h4-7H,1-3H3,(H2,15,16,17,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.				Bioorg Med Chem Lett 7: 417-420 (1997) Article DOI: 10.1016/S0960-894X(97)00034-6 BindingDB Entry DOI: 10.7270/Q2J966VN
					More data for this Ligand-Target Pair