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SMILES: COc1cc2ncnc(Nc3ccc4CCCc4c3)c2cc1OC

InChI Key: InChIKey=ROWZBCBRQQSSRI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50291098 ((6,7-Dimethoxy-quinazolin-4-yl)-indan-5-yl-amine; ...) Show SMILES COc1cc2ncnc(Nc3ccc4CCCc4c3)c2cc1OC Show InChI InChI=1S/C19H19N3O2/c1-23-17-9-15-16(10-18(17)24-2)20-11-21-19(15)22-14-7-6-12-4-3-5-13(12)8-14/h6-11H,3-5H2,1-2H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor autophosphorylation.				Bioorg Med Chem Lett 7: 417-420 (1997) Article DOI: 10.1016/S0960-894X(97)00034-6 BindingDB Entry DOI: 10.7270/Q2J966VN
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50291098 ((6,7-Dimethoxy-quinazolin-4-yl)-indan-5-yl-amine; ...) Show SMILES COc1cc2ncnc(Nc3ccc4CCCc4c3)c2cc1OC Show InChI InChI=1S/C19H19N3O2/c1-23-17-9-15-16(10-18(17)24-2)20-11-21-19(15)22-14-7-6-12-4-3-5-13(12)8-14/h6-11H,3-5H2,1-2H3,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.				Bioorg Med Chem Lett 7: 417-420 (1997) Article DOI: 10.1016/S0960-894X(97)00034-6 BindingDB Entry DOI: 10.7270/Q2J966VN
					More data for this Ligand-Target Pair