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SMILES: Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)c1\C=N\Nc1ccc(cc1)[N+]([O-])=O)-c1ccccc1

InChI Key: InChIKey=GSPRJOUPYFHVOE-FDAWAROLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291374   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase Chk2


(Homo sapiens (Human))		BDBM50291374
PNG
(CHEMBL4167099)
Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)c1\C=N\Nc1ccc(cc1)[N+]([O-])=O)-c1ccccc1
Show InChI InChI=1S/C30H22N8O5/c1-19-26(18-31-34-21-9-11-23(12-10-21)37(39)40)30(36(35-19)22-5-3-2-4-6-22)43-25-14-7-20(8-15-25)29-32-27-16-13-24(38(41)42)17-28(27)33-29/h2-18,34H,1H3,(H,32,33)/b31-18+
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PC cid
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Similars
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



National Research Centre

Curated by ChEMBL


Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis

Eur J Med Chem 144: 859-873 (2018)


Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1
More data for this
Ligand-Target Pair