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BDBM50291670 CHEMBL4175147

SMILES: CCCCC1=N\C(=C/c2ccccc2Br)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn(n1)C(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=YQPANHWTSULFKY-SLSZCLEPSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291670   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))		BDBM50291670
PNG
(CHEMBL4175147)
Show SMILES CCCCC1=N\C(=C/c2ccccc2Br)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn(n1)C(c1ccccc1)(c1ccccc1)c1ccccc1 |t:4|
Show InChI InChI=1S/C47H39BrN6O/c1-2-3-27-44-49-43(32-36-17-13-16-26-42(36)48)46(55)53(44)33-34-28-30-35(31-29-34)40-24-14-15-25-41(40)45-50-52-54(51-45)47(37-18-7-4-8-19-37,38-20-9-5-10-21-38)39-22-11-6-12-23-39/h4-26,28-32H,2-3,27,33H2,1H3/b43-32-
PDB

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Article
PubMed
 317n/an/an/an/an/an/an/an/a



Bahcesehir University (BAU)

Curated by ChEMBL


Assay Description
Displacement of [125I-Sar1-Ile8]-Ang2 from human angiotensin 2 receptor type 1 receptor expressed in HEK293 cells after 1 hr by gamma counting analys...

Eur J Med Chem 145: 273-290 (2018)


Article DOI: 10.1016/j.ejmech.2017.12.021
BindingDB Entry DOI: 10.7270/Q2639S81
More data for this
Ligand-Target Pair