BDBM50291679 4-Amino-2,2-dimethyl-chroman-4,7-dicarboxylic acid::CHEMBL278949
SMILES: CC1(C)CC(N)(C(O)=O)c2ccc(cc2O1)C(O)=O
InChI Key: InChIKey=AADMYFPTDLOICR-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor (RAT) | BDBM50291679 (4-Amino-2,2-dimethyl-chroman-4,7-dicarboxylic acid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 9.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 1 was determined | Bioorg Med Chem Lett 7: 1195-1198 (1997) Article DOI: 10.1016/S0960-894X(97)00177-7 BindingDB Entry DOI: 10.7270/Q2MC901V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Rattus norvegicus) | BDBM50291679 (4-Amino-2,2-dimethyl-chroman-4,7-dicarboxylic acid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 2 was determined | Bioorg Med Chem Lett 7: 1195-1198 (1997) Article DOI: 10.1016/S0960-894X(97)00177-7 BindingDB Entry DOI: 10.7270/Q2MC901V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor (Rattus norvegicus (Rat)) | BDBM50291679 (4-Amino-2,2-dimethyl-chroman-4,7-dicarboxylic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 3.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 5 was determined | Bioorg Med Chem Lett 7: 1195-1198 (1997) Article DOI: 10.1016/S0960-894X(97)00177-7 BindingDB Entry DOI: 10.7270/Q2MC901V | |||||||||||
More data for this Ligand-Target Pair |