BindingDB logo
myBDB logout

BDBM50292443 3,4,5-tribromo-2-(2', 4'-dibromo-phenoxy)phenol::3,4,5-tribromo-2-(2,4-dibromophenoxy)phenol::CHEMBL464577

SMILES: Oc1cc(Br)c(Br)c(Br)c1Oc1ccc(Br)cc1Br

InChI Key: InChIKey=LNZHBUPVHNJGJG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292443   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))
BDBM50292443
PNG
(3,4,5-tribromo-2-(2', 4'-dibromo-phenoxy)phenol | ...)
Show SMILES Oc1cc(Br)c(Br)c(Br)c1Oc1ccc(Br)cc1Br
Show InChI InChI=1S/C12H5Br5O2/c13-5-1-2-9(6(14)3-5)19-12-8(18)4-7(15)10(16)11(12)17/h1-4,18H
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.25E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of Bak binding to Mcl-1 by FRET assay


J Nat Prod 72: 443-9 (2009)


Article DOI: 10.1021/np800737z
BindingDB Entry DOI: 10.7270/Q2XW4NMD
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase


(Homo sapiens (Human))
BDBM50292443
PNG
(3,4,5-tribromo-2-(2', 4'-dibromo-phenoxy)phenol | ...)
Show SMILES Oc1cc(Br)c(Br)c(Br)c1Oc1ccc(Br)cc1Br
Show InChI InChI=1S/C12H5Br5O2/c13-5-1-2-9(6(14)3-5)19-12-8(18)4-7(15)10(16)11(12)17/h1-4,18H
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of 15-lipoxygenase


J Nat Prod 58: 1384-1391 (1995)


Article DOI: 10.1021/np50123a008
BindingDB Entry DOI: 10.7270/Q22B8Z26
More data for this
Ligand-Target Pair