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SMILES: Oc1ccc(\C=C(\C#N)C(=O)NC2CCCCC2)cc1O

InChI Key: InChIKey=XMFXBOGXTNAKKW-WQLSENKSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292524   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50292524
PNG
(2-cyano-N-cyclohexyl-3-(3,4-dihydroxyphenyl)acryla...)
Show SMILES Oc1ccc(\C=C(\C#N)C(=O)NC2CCCCC2)cc1O
Show InChI InChI=1S/C16H18N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h6-9,13,19-20H,1-5H2,(H,18,21)/b12-8-
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MMDB

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Similars
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of EGFR in human A431 cells

J Nat Prod 55: 1529-1560 (1992)


Article DOI: 10.1021/np50089a001
BindingDB Entry DOI: 10.7270/Q2J966CC
More data for this
Ligand-Target Pair