null
SMILES: CO[C@H]1O[C@H](CNS(=O)(=O)CCN)[C@@H](O)[C@H](O)[C@H]1O
InChI Key: InChIKey=OYQRHZKVTNWARB-ZEBDFXRSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase (Plasmodium falciparum (isolate 3D7)) | BDBM50292583![]() (CHEMBL4164794) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by spectrofluorimetric analysis | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucose-6-phosphate 1-dehydrogenase (Homo sapiens (Human)) | BDBM50292583![]() (CHEMBL4164794) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr... | Eur J Med Chem 146: 108-122 (2018) Article DOI: 10.1016/j.ejmech.2018.01.044 BindingDB Entry DOI: 10.7270/Q2CN76FJ | |||||||||||
More data for this Ligand-Target Pair |