BDBM50292771 17beta-Hydroxy-11beta-[4-(1-oxo-4-carboxy-N-methylbutylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one::CHEMBL500992

SMILES: CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C(=O)CCCC(O)=O

InChI Key: InChIKey=HDGGCJDELDDYQH-SBMMGGBVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50292771 (17beta-Hydroxy-11beta-[4-(1-oxo-4-carboxy-N-methyl...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C(=O)CCCC(O)=O |r,c:18,t:11| Show InChI InChI=1S/C33H39NO5/c1-4-17-33(39)18-16-28-26-14-10-22-19-24(35)13-15-25(22)31(26)27(20-32(28,33)2)21-8-11-23(12-9-21)34(3)29(36)6-5-7-30(37)38/h8-9,11-12,19,26-28,39H,5-7,10,13-16,18,20H2,1-3H3,(H,37,38)/t26-,27+,28-,32-,33-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...				J Med Chem 52: 1268-74 (2010) Article DOI: 10.1021/jm800985z BindingDB Entry DOI: 10.7270/Q27S7PPM
					More data for this Ligand-Target Pair