BDBM50292772 17beta-Hydroxy-11beta-[4-(1-oxo-5-carboxy-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one::CHEMBL505267

SMILES: CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C(=O)CCCCC(O)=O

InChI Key: InChIKey=KPKMRAJDYFOVTK-BDOGIOJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50292772 (17beta-Hydroxy-11beta-[4-(1-oxo-5-carboxy-N-methyl...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C(=O)CCCCC(O)=O |r,c:18,t:11| Show InChI InChI=1S/C34H41NO5/c1-4-18-34(40)19-17-29-27-15-11-23-20-25(36)14-16-26(23)32(27)28(21-33(29,34)2)22-9-12-24(13-10-22)35(3)30(37)7-5-6-8-31(38)39/h9-10,12-13,20,27-29,40H,5-8,11,14-17,19,21H2,1-3H3,(H,38,39)/t27-,28+,29-,33-,34-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...				J Med Chem 52: 1268-74 (2010) Article DOI: 10.1021/jm800985z BindingDB Entry DOI: 10.7270/Q27S7PPM
					More data for this Ligand-Target Pair