BDBM50292782 17beta-Hydroxy-11beta-{4-[11-carboxy-1,13-dimethyl-2,9-dioxo-1,3,10-triaza-tetradecyl]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one::CHEMBL461357

SMILES: CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C(=O)NCCCCCC(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key: InChIKey=DYWZJBIJXQNKMB-KHKJJKDASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50292782 (17beta-Hydroxy-11beta-{4-[11-carboxy-1,13-dimethyl...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C(=O)NCCCCCC(=O)N[C@@H](CC(C)C)C(O)=O |r,c:18,t:11| Show InChI InChI=1S/C41H55N3O6/c1-6-20-41(50)21-19-34-32-17-13-28-24-30(45)16-18-31(28)37(32)33(25-40(34,41)4)27-11-14-29(15-12-27)44(5)39(49)42-22-9-7-8-10-36(46)43-35(38(47)48)23-26(2)3/h11-12,14-15,24,26,32-35,50H,7-10,13,16-19,21-23,25H2,1-5H3,(H,42,49)(H,43,46)(H,47,48)/t32-,33+,34-,35-,40-,41-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...				J Med Chem 52: 1268-74 (2010) Article DOI: 10.1021/jm800985z BindingDB Entry DOI: 10.7270/Q27S7PPM
					More data for this Ligand-Target Pair