BDBM50293785 CHEMBL562236::Ethyl 4-[3-(2,4-dichlorobenzylcarbamoyl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-7-yl)]piperazine-1-carboxylate

SMILES: CCOC(=O)N1CCN(CC1)c1cc2n(CC)cc(C(=O)NCc3ccc(Cl)cc3Cl)c(=O)c2cc1F

InChI Key: InChIKey=XYXRKXIPTLHUGH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycoprotein G (Nipah virus)	BDBM50293785 (CHEMBL562236 | Ethyl 4-[3-(2,4-dichlorobenzylcarba...) Show SMILES CCOC(=O)N1CCN(CC1)c1cc2n(CC)cc(C(=O)NCc3ccc(Cl)cc3Cl)c(=O)c2cc1F Show InChI InChI=1S/C26H27Cl2FN4O4/c1-3-31-15-19(25(35)30-14-16-5-6-17(27)11-20(16)28)24(34)18-12-21(29)23(13-22(18)31)32-7-9-33(10-8-32)26(36)37-4-2/h5-6,11-13,15H,3-4,7-10,14H2,1-2H3,(H,30,35)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
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