BDBM50294129 2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfonamido)-N-hydroxyacetamide::CHEMBL561039

SMILES: CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C

InChI Key: InChIKey=KJDPTHLLJDQIMT-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50294129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50294129 (2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfo...) Show SMILES CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C Show InChI InChI=1S/C17H22N2O5S2/c1-4-13-5-7-14(8-6-13)15-9-10-17(25-15)26(22,23)19(24-12(2)3)11-16(20)18-21/h5-10,12,21H,4,11H2,1-3H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9				J Med Chem 52: 4757-73 (2009) Article DOI: 10.1021/jm900261f BindingDB Entry DOI: 10.7270/Q2JW8DXN
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50294129 (2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfo...) Show SMILES CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C Show InChI InChI=1S/C17H22N2O5S2/c1-4-13-5-7-14(8-6-13)15-9-10-17(25-15)26(22,23)19(24-12(2)3)11-16(20)18-21/h5-10,12,21H,4,11H2,1-3H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14				J Med Chem 52: 4757-73 (2009) Article DOI: 10.1021/jm900261f BindingDB Entry DOI: 10.7270/Q2JW8DXN
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50294129 (2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfo...) Show SMILES CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C Show InChI InChI=1S/C17H22N2O5S2/c1-4-13-5-7-14(8-6-13)15-9-10-17(25-15)26(22,23)19(24-12(2)3)11-16(20)18-21/h5-10,12,21H,4,11H2,1-3H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP1				J Med Chem 52: 4757-73 (2009) Article DOI: 10.1021/jm900261f BindingDB Entry DOI: 10.7270/Q2JW8DXN
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50294129 (2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfo...) Show SMILES CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C Show InChI InChI=1S/C17H22N2O5S2/c1-4-13-5-7-14(8-6-13)15-9-10-17(25-15)26(22,23)19(24-12(2)3)11-16(20)18-21/h5-10,12,21H,4,11H2,1-3H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP13-mediated collagen degradation by SDS-PAGE				J Med Chem 52: 4757-73 (2009) Article DOI: 10.1021/jm900261f BindingDB Entry DOI: 10.7270/Q2JW8DXN
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50294129 (2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfo...) Show SMILES CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C Show InChI InChI=1S/C17H22N2O5S2/c1-4-13-5-7-14(8-6-13)15-9-10-17(25-15)26(22,23)19(24-12(2)3)11-16(20)18-21/h5-10,12,21H,4,11H2,1-3H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP3				J Med Chem 52: 4757-73 (2009) Article DOI: 10.1021/jm900261f BindingDB Entry DOI: 10.7270/Q2JW8DXN
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50294129 (2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfo...) Show SMILES CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C Show InChI InChI=1S/C17H22N2O5S2/c1-4-13-5-7-14(8-6-13)15-9-10-17(25-15)26(22,23)19(24-12(2)3)11-16(20)18-21/h5-10,12,21H,4,11H2,1-3H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP8				J Med Chem 52: 4757-73 (2009) Article DOI: 10.1021/jm900261f BindingDB Entry DOI: 10.7270/Q2JW8DXN
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50294129 (2-(5-(4-Ethylphenyl)-N-isopropoxythiophene-2-sulfo...) Show SMILES CCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N(CC(=O)NO)OC(C)C Show InChI InChI=1S/C17H22N2O5S2/c1-4-13-5-7-14(8-6-13)15-9-10-17(25-15)26(22,23)19(24-12(2)3)11-16(20)18-21/h5-10,12,21H,4,11H2,1-3H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2				J Med Chem 52: 4757-73 (2009) Article DOI: 10.1021/jm900261f BindingDB Entry DOI: 10.7270/Q2JW8DXN
					More data for this Ligand-Target Pair