BDBM50294740 3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-phenyl}-8-(trifluoromethyl)cinnoline::CHEMBL554508

SMILES: Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(cccc34)C(F)(F)F)c12

InChI Key: InChIKey=QJFZBMOXZHRSFQ-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50294740 (3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...) Show SMILES Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(cccc34)C(F)(F)F)c12 Show InChI InChI=1S/C32H24F3N3O/c1-38-17-16-22-10-5-12-24(31(22)38)20-39-25-13-6-11-23(19-25)29-26-14-7-15-27(32(33,34)35)30(26)37-36-28(29)18-21-8-3-2-4-9-21/h2-17,19H,18,20H2,1H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...				Bioorg Med Chem 17: 3519-27 (2009) Article DOI: 10.1016/j.bmc.2009.04.012 BindingDB Entry DOI: 10.7270/Q2T72HH5
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50294740 (3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...) Show SMILES Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(cccc34)C(F)(F)F)c12 Show InChI InChI=1S/C32H24F3N3O/c1-38-17-16-22-10-5-12-24(31(22)38)20-39-25-13-6-11-23(19-25)29-26-14-7-15-27(32(33,34)35)30(26)37-36-28(29)18-21-8-3-2-4-9-21/h2-17,19H,18,20H2,1H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.32E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiv...				Bioorg Med Chem 17: 3519-27 (2009) Article DOI: 10.1016/j.bmc.2009.04.012 BindingDB Entry DOI: 10.7270/Q2T72HH5
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50294740 (3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...) Show SMILES Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(cccc34)C(F)(F)F)c12 Show InChI InChI=1S/C32H24F3N3O/c1-38-17-16-22-10-5-12-24(31(22)38)20-39-25-13-6-11-23(19-25)29-26-14-7-15-27(32(33,34)35)30(26)37-36-28(29)18-21-8-3-2-4-9-21/h2-17,19H,18,20H2,1H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRalpha ligand binding domain (197-447) expressed in Escherichia ...				Bioorg Med Chem 17: 3519-27 (2009) Article DOI: 10.1016/j.bmc.2009.04.012 BindingDB Entry DOI: 10.7270/Q2T72HH5
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50294740 (3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-ph...) Show SMILES Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(cccc34)C(F)(F)F)c12 Show InChI InChI=1S/C32H24F3N3O/c1-38-17-16-22-10-5-12-24(31(22)38)20-39-25-13-6-11-23(19-25)29-26-14-7-15-27(32(33,34)35)30(26)37-36-28(29)18-21-8-3-2-4-9-21/h2-17,19H,18,20H2,1H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant N-terminal biotinylated tagged LXRbeta ligand binding domain (154-461) expressed in Escherichia c...				Bioorg Med Chem 17: 3519-27 (2009) Article DOI: 10.1016/j.bmc.2009.04.012 BindingDB Entry DOI: 10.7270/Q2T72HH5
					More data for this Ligand-Target Pair