BindingDB logo
myBDB logout

null

SMILES: CC(C(=O)NS(C)(=O)=O)c1ccccc1Nc1c(Cl)cccc1Cl

InChI Key: InChIKey=ZNEWAVGEUAWOBQ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295268   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-8


(Homo sapiens (Human))		BDBM50295268
PNG
(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(methyls...)
Show SMILES CC(C(=O)NS(C)(=O)=O)c1ccccc1Nc1c(Cl)cccc1Cl
Show InChI InChI=1S/C16H16Cl2N2O3S/c1-10(16(21)20-24(2,22)23)11-6-3-4-9-14(11)19-15-12(17)7-5-8-13(15)18/h3-10,19H,1-2H3,(H,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Grupo Uriach

Curated by ChEMBL


Assay Description
Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay

Bioorg Med Chem Lett 19: 4026-30 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.027
BindingDB Entry DOI: 10.7270/Q2V124TW
More data for this
Ligand-Target Pair