BDBM50295297 CHEMBL559092::trans-3-((1R,2R)-2-((dimethylamino)methyl)cyclopentyl)-1H-indole-5-carbonitrile

SMILES: CN(C)C[C@@H]1CCC[C@H]1c1c[nH]c2ccc(cc12)C#N

InChI Key: InChIKey=RXJIAQGHWRMBEZ-UONOGXRCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50295297 (CHEMBL559092 | trans-3-((1R,2R)-2-((dimethylamino)...) Show SMILES CN(C)C[C@@H]1CCC[C@H]1c1c[nH]c2ccc(cc12)C#N |r| Show InChI InChI=1S/C17H21N3/c1-20(2)11-13-4-3-5-14(13)16-10-19-17-7-6-12(9-18)8-15(16)17/h6-8,10,13-14,19H,3-5,11H2,1-2H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers SquibbPharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4031-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.026 BindingDB Entry DOI: 10.7270/Q2Q81D3K
					More data for this Ligand-Target Pair