BDBM50295639 (1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-hydroxy-1-isopropenyl-12a-methyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one::CHEMBL561460

SMILES: CN(C)c1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@@]2(O)C(C)=C)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key: InChIKey=HDCJFWTUMAKTNA-DCJUPOQYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50295639 ((1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-...) Show SMILES CN(C)c1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@@]2(O)C(C)=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:27,34| Show InChI InChI=1S/C29H37NO3/c1-18(2)29(32)15-14-25-24-12-8-20-16-22(31)11-13-23(20)26(24)27(33-17-28(25,29)3)19-6-9-21(10-7-19)30(4)5/h6-7,9-10,16,24-25,27,32H,1,8,11-15,17H2,2-5H3/t24-,25-,27+,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50295639 ((1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-...) Show SMILES CN(C)c1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@@]2(O)C(C)=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:27,34| Show InChI InChI=1S/C29H37NO3/c1-18(2)29(32)15-14-25-24-12-8-20-16-22(31)11-13-23(20)26(24)27(33-17-28(25,29)3)19-6-9-21(10-7-19)30(4)5/h6-7,9-10,16,24-25,27,32H,1,8,11-15,17H2,2-5H3/t24-,25-,27+,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced transcription after 16 hrs by glucocor...				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair