null

SMILES: COc1ccc2[nH]c(CN(C)c3ccc(cc3)C(F)(F)F)c(CCNC(C)=O)c2c1

InChI Key: InChIKey=WQYNWUPUMDNUPV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melatonin receptor type 1B (Homo sapiens (Human))	BDBM50295870 (CHEMBL563847 | N-{2-(5-Methoxy-2-({[methyl[4-(trif...) Show SMILES COc1ccc2[nH]c(CN(C)c3ccc(cc3)C(F)(F)F)c(CCNC(C)=O)c2c1 Show InChI InChI=1S/C22H24F3N3O2/c1-14(29)26-11-10-18-19-12-17(30-3)8-9-20(19)27-21(18)13-28(2)16-6-4-15(5-7-16)22(23,24)25/h4-9,12,27H,10-11,13H2,1-3H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in CHO cells by gamma counting				Bioorg Med Chem 17: 4583-94 (2009) Article DOI: 10.1016/j.bmc.2009.04.068 BindingDB Entry DOI: 10.7270/Q29W0FHG
					More data for this Ligand-Target Pair
Melatonin receptor type 1A (Homo sapiens (Human))	BDBM50295870 (CHEMBL563847 | N-{2-(5-Methoxy-2-({[methyl[4-(trif...) Show SMILES COc1ccc2[nH]c(CN(C)c3ccc(cc3)C(F)(F)F)c(CCNC(C)=O)c2c1 Show InChI InChI=1S/C22H24F3N3O2/c1-14(29)26-11-10-18-19-12-17(30-3)8-9-20(19)27-21(18)13-28(2)16-6-4-15(5-7-16)22(23,24)25/h4-9,12,27H,10-11,13H2,1-3H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in CHO cells by gamma counting				Bioorg Med Chem 17: 4583-94 (2009) Article DOI: 10.1016/j.bmc.2009.04.068 BindingDB Entry DOI: 10.7270/Q29W0FHG
					More data for this Ligand-Target Pair